Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats -
Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site | eLife
κ-opioid receptor - Wikipedia
Self-Administered Heroin and Cocaine Combinations in the Rat: Additive Reinforcing Effects—Supra-Additive Effects on Nucleus Accumbens Extracellular Dopamine | Neuropsychopharmacology
Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity | Journal of Medicinal Chemistry
Locomotor activity: A distinctive index in morphine self-administration in rats | PLOS ONE
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria | Science Signaling
Hot topics in opioid pharmacology: mixed and biased opioids - British Journal of Anaesthesia
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists
Interactions between Kappa Opioid Agonists and Cocaine: Preclinical Studies - MELLO - 2000 - Annals of the New York Academy of Sciences - Wiley Online Library
Molecules | Free Full-Text | Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents | HTML
Kappa-opioid receptor activation reinstates nicotine self-administration in mice - ScienceDirect
Morphine self-administration (MSA) is increased in irradiated rats. (a)... | Download Scientific Diagram
Systemic nicotine enhances opioid self-administration and modulates the formation of opioid-associated memories partly through actions within the insular cortex | Scientific Reports
Frontiers | Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex